Neck relief ... sort of

This guitar is a real wonder. Strangest acting truss rod I have ever seen.
It befuddled me to know end when doing initial set-up several months ago but I got it all set-up nice. So, heres my situation ... I changed out the pickups the other day, going to a set of chrome covered buckers from the original black, un covered pick-ups. With the slightly larger size of the new pups with the covers, the bridge pup wouldnt sit level. Turns out that the pickup ring wasnt centered in the route so the side of the pickup was up against the wall of the pickup route causing it to not sit level. So, I remove the strings again today, fill the original holes and redrill to center the mounting ring and the pup. That went fine but had the strings off for better than 3 hours. Got everything buttoed up and restrung and the neck relief is now out of wack again. So my question is this ... will the neck generally go back to where it was before? How long should I give it before I know whether I need to mess with the relief again ... 24 hours? 48? ... Definitely do not want to mess with this particular truss rod again if I dont have too. So, how long to wait before I know for sure whether it will return or I if have to adjust again? THX